This error might happen if the application pool for the web site account password is changed and not updated,
Open the IIS Manager
Go to Application Pools 
Select the Application Pool related to the website. 
 Right Click and select Advanced Settings
 under Process Model Select Identity
 Click on ... button next to the the user name
 Click on "Set"
 Enter the user name and new password
 Click Ok and close the popup windoos
 Start the application Pool 
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